How High Doses of Ibuprofen May Impact Male Infertility

How High Doses of Ibuprofen May Impact Male Infertility

"Our immediate concern is for the fertility of men who use these drugs for a long time", study author David Møbjerg Kristensen, of the University of Copenhagen, told the newspaper.

According to scientists, these men may also experience erectile dysfunction, fatigue, and muscle wastage, as prolonged ibuprofen usage disrupted testosterone hormones.

The small study, which was published yesterday (Jan. 8) in the journal Proceedings of the National Academy of Sciences, found that men who took 1,200 milligrams of ibuprofen a day for six weeks developed a hormonal condition that is linked with reproductive problems.

Researchers conducted a relatively small study that included men aged 18 to 35 and found that those who used the common over-the-counter drug developed hormonal imbalances that can cause a reduction in fertility, CBS news reported. 17 men were given a daily dose of 1200mg if ibuprofen.

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Before you go raid your medicine cabinet, Advil and Motrin are two brand names for ibuprofen. The condition arises when the body has to boost levels of testosterone because normal production in the testes has fallen.

The researchers, from Denmark, France, and China, concluded that taking ibuprofen increases the risk of a condition known as compensated hypogonadism. As this happened, the ratio of testosterone to luteinizing hormones decreased. "Taken together, these in vivo data suggest that ibuprofen induced a state of compensated hypogonadism during the trial..." the study states.

On a positive note, the disorder remains totally reversible when the ibuprofen is taken over a brief period, Bernard Jégou, a co-author at French National Institute of Health and Medical Research, told CNN. Before he stepped down in November 2016 he asked players about their use of over-the-counter painkillers and found that almost half of those who played in the past three World Cups took anti-inflammatory drugs, such as ibuprofen, every day. Jegou, however, warned against taking the drug for months beyond what it necessary. "These compounds are good painkillers, but a certain amount of people in society use them without thinking of them as proper medicines". "The risk is greater than the benefit".

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